Publications Archive

BICOLL NEWS – 2018

Welcome to the 2018 edition of Bicoll News. For those familiar with Bicoll’s previous yearly newsletters, we would like to introduce the good “new-old” style of a snapshot of topics concerning our last year that aims to provide an overview of our services and capabilities. We thank you, our loyal customers, partners and friends for …

Company Teaser in English and Japanese

RELIABLE RESEARCH PARTNER WITH EXPERTISE, KNOW-HOW AND EXPERIENCE IN DRUG DISCOVERY FROM PLANT NATURAL PRODUCTS Read more in a new company teaser 植物天然由来物を用いた創薬における専門知識、 ノウハウ、経験の豊富な信頼できる共同研究パートナー 日本語版はこちらからダウンロードして下さい    

Public impulses to support biotechnology: Healthcare system in China

“Öffentlich getriebene Impulse zur Unterstützung der Biotechnologie”, M. Lamottke, Y. Zhou, “Das Gesundheitswesen in China” Medizinisch Wissentschaftliche Verlagsgesellschaft, 2017, Pp. 165-179 ISBN: 978-3-95466-303-3 „Das Gesundheitswesen in China“ schildert die systembedingten und kulturellen Hintergründe des Umgangs mit Gesundheit und Krankheit. Es zeigt die Zwei-Klassen-Medizin in China als Konsequenz der Wohlstandsunterschiede und des ungleichen Versicherungsschutzes der Patienten. …

MicroRNAs in epilepsy: pathophysiology and clinical utility

Prof. David C. Henshall, Prof. Hajo M. Hamer, MD, Prof. R. Jeroen Pasterkamp, PhD, Prof. David B. Goldstein, PhD, Prof. Jørgen Kjems, PhD, Prof. Jochen H. M. Prehn, PhD, Stephanie Schorge, PhD, Kai Lamottke, PhD, Felix Rosenow, MD, THE LANCET Neurology, Dec. 2016, DOI: http://dx.doi.org/10.1016/S1474-4422(16)30246. Temporal lobe epilepsy is a common and frequently intractable seizure …

Evaluation of the Anti-inflammatory and Anti-oxidative Potential of Four Fern Species from China Intended for Use as Food Supplements

C. Dion, C. Haug, H. Guan, C. Ripoll, P. Spiteller, A. Coussaert, E. Boulet, D. Schmidt, J. Wei, Y. Zhou, K. Lamottke, Natural product communications, 10(4), 597-603, April 2015. Inflammation plays a major role in many diseases, for instance in arteriosclerosis, rheumatoid arthritis, autoimmune disorders and cancer. Since many plants contain compounds with anti-inflammatory activity, …

The Identification of Naturally Occurring Neoruscogenin as a Bioavailable, Potent and High-Affinity Agonist of the Nuclear Receptor RORa (NR1F1)

S. Helleboid, C. Haug, K. Lamottke, Y. Zhou, J. Wei, S. Daix, L. Cambula, G. Rigou, D. W. Hum, R. Walczak, Journal of Biomolecular Screening, Jul 2013, DOI: 10.1177/1087057113497095. New target validation has always been a challenge for the pharmaceutical industry with respect to the potential therapeutic value. Information obtained through genetic gain- and/or loss-of-function …

Bicoll News 2012

Bicoll Newsletter Edition 2012: Bicoll as Partner of a € 2.7 M European-Funded EuroTransBio Program Nutraceutical Research Alliance with Naturalpha (France) New Service Platform based on Innovative Fragment Library Concept Ready to Market What to expect from Bicoll in 2012 – Extension of Bicoll_News_2012: NP Synthesis and NP Isolation on Demand PDF-Download Bicoll News 2012 …

Working in the Chinese Drug Industry

Chemical & Engineering News, 89(7), February 14, 2011 “At Bicoll Biotechnology in Shanghai’s Zhangjiang Hi-Tech Park, Managing Director Kai Lamottke is skeptical that the Chinese drug industry has openings for a sizable contingent of scientists from abroad. “The scientists with foreign experience represent, in percentage terms, a tiny minority of employees in the Chinese pharmaceutical …

The roots of innovation – Can we afford to turn away from natural product drug discovery research?

European Biopharmaceutical Review, January 2011, p.52 Kai Lamottke at Bicoll GmbH, Christophe Ripoll at Naturalpha and Robert Walczak at Genfit SA ask if the biotech industry can afford to turn away from natural product drug discovery research. One of the most successful sources of scaffolds for the identification and development of new drugs are natural …