Evolution Has The Solution

Natural Compound Libraries for

Pharmaceuticals - Cosmetics - Agriculture - Nutraceuticals


We Envision Molecules of the Future – and Help You Make Them


Bicoll provides an efficient and multi-disciplinary technology approach to the discovery of novel potent molecules for the pharmaceutical, nutraceutical, and agricultural industry. Our proprietary small molecule property-based isolation technology enables an efficient Hit to Lead workflow for natural compounds. Bicoll’s plant-based small molecule libraries have been proven in a wide range of applications as documented by peer-reviewed publications and patents.


Besides comprehensive partnerships we offer services for individual steps of the Hit-to-Lead process using plant-derived natural compounds on FTE or FFS basis:

  • Custom Natural Product Libraries
  • Medicinal Chemistry
  • Chemical Structure Elucidation
  • Custom Compound Synthesis
  • Synthesis Strategy Consulting
  • Scale up services (500 g – 5 kg)


Bicoll is in a unique position at the interface of plant-based natural compounds and medicinal chemistry. Our two decades of experience partnering with industry and research worldwide to bring scientific excellence and customer service make us a trusted and reliable business partner for organizations. Increase the quantity and quality of your lead candidate portfolio by partnering with us.

Bicoll Celebrates 20th Anniversary

2020 was certainly a different, by all measures, and challenging year for many. Despite all, we had a reason to be thankful and to celebrate the 20th anniversary of Bicoll! On November 29th, 2000 we embarked on this exciting journey to deliver research services, to establish Bicoll’s natural compound libraries, backed by strong medicinal chemistry. We are continuing our promises to provide well researched, validated, and actionable insights to help our partners to develop new effective drugs based on natural compounds. Here we would like to take a moment to celebrate, reflect, and summarize the achievements of the last two decades.

Latest News

  • Fractionation and Extraction Optimization of Compounds
    New publication on molecules “Fractionation and Extraction Optimization of Potentially Valuable Compounds and Their Profiling in Six Varieties of Two Nicotiana Species”. There is an increasingly urgent call to shift industrial processes from fossil fuel feedstock to sustainable bio-based resources. Such a transformation can be driven by traditionally used plants that are able to produce …

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  • Cybersecurity in Biotech and the Pharmaceutical Industry
    In this fireside chat, Maria Lamottke talks to Christoph Eicken and focuses on the aspects of cybersecurity for biotech and pharmaceutical companies. Are there any special considerations when it comes to biotech and cybersecurity? Who is responsible for establishing and implementing a cybersecurity strategy? What are cost factors? Do you really need to worry about …

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  • Bio-Convention 2022
    Bicoll joins Bio 2022 to discuss research partnership opportunities in person. Visit us at German Pavilion – Booth 4607. #BIO2022 is back in-person! As there is no substitute for in-person collaboration, BIO is back this year offering ample opportunities to connect with peers and those who can help you achieve your business goals. Check out …

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Our Clients & Partners

We support decision makers across DIFFERENT research AREAS to make data-driven decisions.

Industry Research Partner Lab

Industry Partners

We value our corporate partners in a range of industries such as pharmaceuticals, nutrition, food additives, agriculture, and cosmetics. Covering all continents and corporate sizes, we offer you the best solution for your organization’s needs.

Academic Partners

Academic partners and research groups will find a suitable and flexible partner in Bicoll. Working together with a number of universities and research organizations we know how to best address your needs, achieve fast results and prepare publications.

Academic Research Partner Chemistry Lab

Our Trademarks

Bicoll owns several trademarks for proprietary processes in our Hit-to-Lead workflow :

  • BILOBAC N™ is a small molecule library.
  • BIFRAC N™ is Bicoll’s proprietary separation system.
  • BIPRESELECT™ – preselection technique, which is one of the few existing techniques in early drug development according to physicochemical properties, e.g. logP, mol weight, solubility.
  • Bicoll Plant Profiles™ are plant-based fine fractions, fractionated by Bicoll’s innovative isolation system BIFRAC N™.

Global Partnerships