Nuclear Receptor RORa

Bicoll announces a fast small molecule ligand validation method for orphan targets

August 29, 2013

Munich (Germany) – August 29, 2013 – BICOLL Group announces today the successful application of its technology for the identification of ligands of a specific orphan target. As described in a new publication in the Journal of Biomolecular Screening, a …

The Identification of Naturally Occurring Neoruscogenin as a Bioavailable, Potent and High-Affinity Agonist of the Nuclear Receptor RORa (NR1F1)

July 31, 2013

S. Helleboid, C. Haug, K. Lamottke, Y. Zhou, J. Wei, S. Daix, L. Cambula, G. Rigou, D. W. Hum, R. Walczak, Journal of Biomolecular Screening, Jul 2013, DOI: 10.1177/1087057113497095. New target validation has always been a challenge for the pharmaceutical …